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The Trigger: The "Brownout" When your brain's demand for energy outstrips its supply of ATP (cellular fuel), the system panics

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G., Vale Jnior, J

Of special interest are drug substrates with a narrow therapeutic range, such as S-warfarin, tolbutamide and phenytoin, where impaired CYP2C9 metabolic activity might cause difficulties in dose adjustment as well as toxicity (13,14)

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